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LPN Online Programs
in South Carolina

Study nursing theory online — complete your clinical hours at approved healthcare facilities near you in South Carolina.

✅ Accredited Programs 🏥 Local Clinical Placement 💻 Online Theory Coursework ⏱ 11–18 Month Programs

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~$5K
Avg. Program Cost
11–18
Months to Complete
$58K+
Avg. SC LPN Salary
NCLEX-PN
Licensure Exam

Lottery Tuition + MUSC Clinicals: South Carolina's Hybrid LPN Formula

South Carolina's hybrid LPN formula combines two things that rarely go together: free-or-near-free tuition and clinical rotations at a top academic medical center. The SC Lottery Tuition Assistance program covers a significant portion of technical college tuition, and when stacked with Pell Grants, many students complete their entire LPN program with zero out-of-pocket cost. Trident Technical College in Charleston places students at MUSC (Medical University of South Carolina) — one of the best academic medical centers in the Southeast — for clinical rotations. You study pharmacology and care planning online, then walk the halls of a nationally ranked hospital for your hands-on training.

The 16-campus technical college network covers every region of the state. Greenville Technical College serves the booming Upstate where Prisma Health (SC's largest employer) is headquartered and expanding. Midlands Technical College covers Columbia. Florence-Darlington Tech, Spartanburg CC, and Piedmont Tech reach smaller metros and rural areas where hybrid scheduling — online theory plus local clinicals — makes nursing education accessible without relocating. Average salary is $58,430/year with cost of living below the national average. South Carolina is an NLC compact state — your license works in NC, GA, TN, FL, and 35+ other states.

Hybrid LPN Schools in South Carolina

Programs listed offer online or hybrid theory with in-person clinical hours at South Carolina locations. Always verify current enrollment status with each school directly.

Greenville Technical College
📍 Greenville
HybridTechnical College
Length: 12 months Format: Hybrid — online theory + Upstate clinicals Cost: ~$5,400 Clinical: Greenville County hospitals
Midlands Technical College
📍 Columbia
HybridTechnical College
Length: 12 months Format: Hybrid format with online coursework Cost: ~$5,600 Clinical: Richland County partners
Trident Technical College
📍 Charleston
HybridTechnical College
Length: 12 months Format: Hybrid available Cost: ~$5,200 Clinical: Charleston-area facilities

South Carolina LPN Licensure Requirements

RequirementDetail
Governing BodySouth Carolina Board of Nursing
Program AccreditationMust be state board-approved
Minimum Clinical Hours400 hours
Licensure ExamNCLEX-PN (Pearson VUE)
Background CheckRequired prior to clinical placement
CPR CertificationRequired before clinical start
Drug ScreeningRequired by most clinical partner facilities
ImmunizationsPer program/facility requirements

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LPN Salary in South Carolina

Licensed Practical Nurses in South Carolina earn competitive wages. Average annual salary is $58,430 ($28.09/hour). Salaries vary by region, experience, and employer type.

After gaining experience as an LPN, many South Carolina nurses pursue bridge programs. Learn about LPN-to-RN pathways →

Frequently Asked Questions

No. The South Carolina Board of Nursing requires hands-on clinical hours for LPN licensure. Hybrid programs allow the theory portion to be completed online, but clinical rotations must be done in person at approved facilities.
Most hybrid LPN programs in South Carolina range from 11 to 18 months depending on whether you enroll full-time or part-time. Some accelerated tracks can be completed in under a year.
Costs vary widely. Community college programs often run $4,000–$12,000 for in-district students. Private and nationally accredited online programs can range from $18,000–$35,000. Financial aid, grants, and employer tuition assistance may be available.
After graduating from an approved program and applying through the South Carolina Board of Nursing, you schedule your NCLEX-PN exam through Pearson VUE. Testing centers are located in major South Carolina cities.
⚠️ Data Disclaimer: The salary figures, tuition costs, program lengths, and school information on this page are gathered from publicly available sources and are intended as general guidance only. We strive to review and update this information at least once per year, but figures may lag behind current rates. Program availability, accreditation status, and tuition are subject to change — please verify all details directly with the school and the South Carolina Board of Nursing before enrolling. This page may contain affiliate links.

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